Sinopsis Born Again – bercerita tentang dua orang pria dan satu wanita, mereka adalah renkarnasi dari tahun 1980-an. Mereka adalah Kong Ji Chul (1980) / Chun Jong Bum (Jang Ki Yong), Jung Ha Eun (1980) / Jung Sa Bin (Jin Se Yun), dan Cha Hyung Bin (1980) / Kim Soo Hyuk (Lee Soo Hyuk).

Pada tahun 1980-an Kong Ji Chul menyangkal nasibnya menjadi iblis seperti ayahnya, dan di masa kini ia menjadi siswa kedokteran.

Jung Ha Eun di tahun 1980-an menderita kardiomiopati dilatasi, dan di masa kini ia menjadi seorang instruktur arkeologi.

Kemudian, Cha Hyung Bin di tahun 1980-an adalah seorang detektif, dan di masa kini ia menjadi seorang jaksa penuntut.

Synopsis from IMDB
Life, death and second chances take center stage in this story about three people whose intertwined destinies travel through space and time with haunting results. It’s the 1980s and Detective Cha Hyung Bin has devoted his life to criminal justice, and his heart to Ha Eun, a bookshop owner suffering from heart disease who keeps her illness a secret. But Cha Hyung Bin isn’t the only one pining after Ha Eun: serial killer Gong Ji Chul has also fallen in love with her. Their lives collide with tragic results, but 30 years later, they’re reincarnated and fate brings them together again. The more time passes, the more their new lives become tangled in the devastating web of history. Will they manage to escape the past, or be forced to come face to face with it?